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OPCRD Approved Studies

Study Title:

External validation of a clinical prediction model for the diagnosis of asthma in primary care

Approval Date:

02/03/20

Approval Reference:

ADEPT0320

Study Title:

A retrospective observational study on characteristics, treatment patterns, and healthcare resource use of patients with xerostomia in primary care settings using Optimum Patient Care Research Database in United Kingdom

Approval Date:

Requested

Approval Reference:

ADEPT1921

Study Title:

Real-world use of Breztri/Trixeo for the management of COPD in a UK primary care population

Approval Date:

03/31/23

Approval Reference:

ADEPT0123

Study Title:

An observational cohort study to describe intermittent OCS utilisation and its association with adverse outcomes and healthcare resource use and costs in asthma using the OPCRD and CPRD databases.

Approval Date:

09/30/20

Approval Reference:

ADEPT1120

Study Title:

Data Resource Profile: Optimum Patient Care Research Database (OPCRD)

Approval Date:

To be requested

Approval Reference:

ADEPT0121

Study Title:

Asthma epidemiology, prevalence of asthma modifiable factors and healthcare utilisation due to asthma in England, Scotland, Wales, Northern Ireland and the UK

Approval Date:

07/22/20

Approval Reference:

ADEPT0620

Study Title:

AFLOAT: Predicting the risk of Advanced non-alcoholic Fatty Liver Disease in community patients with Abnormal Transaminases

Approval Date:

06/30/22

Approval Reference:

ADEPT0522

Study Title:

Comparative safety of extrafine beclometasone fixed dose combinations (FDC) and fluticasone FDC in COPD

Approval Date:

07/27/20

Approval Reference:

ADEPT0820

Study Title:

PRagmatic EVAluation of a quality Improvement programme for people living with modifiable high-risk COPD (PREVAIL)

Approval Date:

To be requested

Approval Reference:

ADEPT1321

Study Title:

Deriving asthma subtypes from electronic health records using statistical learning

Approval Date:

To be requested

Approval Reference:

ADEPT0619

Study Title:

Gallbladder pathology as an early sign of metachromatic leukodystrophy an exploratory study using electronic health records

Approval Date:

Requested

Approval Reference:

ADEPT1821

Study Title:

Impact of biologic initiation on steroid burden and new-onset of potentially related OCS related risks in patients with severe asthma (SOLAR)

Approval Date:

01/13/23

Approval Reference:

ADEPT1422

Study Title:

Patterns of Management of high-risk COPD in Primary Care, and Opportunities for optimising treatment in the United Kingdom 2000- 2019: Study Protocol

Approval Date:

To be requested

Approval Reference:

ADEPT0221

Study Title:

Development of a prediction model to identify Pompe disease and Fabry disease, based on UK primary care electronic health records

Approval Date:

09/30/20

Approval Reference:

ADEPT1320

Study Title:

Development and evaluation of clinical prediction models to estimate the risk of midgut neuroendocrine tumours using statistical and machine learning approaches: an exploratory study

Approval Date:

09/06/22

Approval Reference:

ADEPT0822

Study Title:

Impact of COVID-19 on asthma exacerbations: protocol for a cohort study in primary care

Approval Date:

08/17/20

Approval Reference:

ADEPT1020a

Study Title:

Unexplored associations with inflammatory skin conditions: a population-based cohort study of the risk of skin cancer, venous thromboembolism, and mental health conditions in atopic dermatitis and vitiligo

Approval Date:

Requested

Approval Reference:

ADEPT0721

Study Title:

Development of a predictive model algorithm to identify patients with hypophosphatasia, using Optimum Patient Care Record Database in United Kingdom

Approval Date:

Received

Approval Reference:

ADEPT1721

Study Title:

Determining the prevalence of severe asthma in children in UK primary care

Approval Date:

10/23/22

Approval Reference:

ADEPT1122

Study Title:

Characteristics, Treatment and Healthcare Resource Utilisation in Patients Diagnosed with Neuropathic or Chronic Pain Using Primary Care Electronic Health Records in the United Kingdom

Approval Date:

07/05/22

Approval Reference:

ADEPT0322

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