What is OPCRD?

The Optimum Patient Care Research Database (OPCRD) is a quality controlled, primary care research database, with a focus on respiratory disease. The OPCRD combines both anonymous routine recorded data with patient reported (questionnaire) data from over 400 UK general practices.


OPCRD has been approved by the Trent Multi Centre Research Ethics Committee for use within Clinical Research. All applications to use the database must be reviewed by the Independent Anonymous Data Ethics Protocols and Transparency ADEPT Committee.

OPCRD data is used in clinical, epidemiological and pharmaceutical research (in both the private and academic sectors). It provides an exclusive insight into the relationship between respiratory disease control and patient reported experience. Data cut from March 2014 illustrates:

Diagram of the composition of the OPCRD database.


The RIRL logo.

Research in Real Life (RiRL) carries out research into the management and treatment of chronic diseases with a particular focus on real-life respiratory research. RiRL studies typically utilise OPCRD data and are designed to address an area of patient care that may be overlooked when considering treatment outcomes in selective randomised trial populations alone.

The REG logo.

The Respiratory Effectiveness Group (REG) is a not-for-profit, investigator-lead initiative established by international experts in real-life and comparative effectiveness research to set the agenda and raise the profile of the field. Access to OPCRD is increasingly provided at reduced cost for these non-commercial research initiatives.

The British Lung Foundation logo.

The British Lung Foundation (BLF) is working alongside OPC to implement their asthma management programme. The aim of the pilot project is to deliver an effective intervention to ensure diagnostic accuracy of asthma in primary care, improve clinical management of risk and control, and improve patient self-management.

The Department of Health logo.

Department of Health (DoH) is currently working with OPC to implement the BLF initiative and funding research on OPCRD to investigate the missed opportunities to diagnose Chronic Obstructive Pulmonary Disease.


The OPCRD has been used as a data source for over 50 publications in reputable journals over the past 5 years.

The Lancet Respiratory Medicine

Primary Care Respiratory Journal

Clinical and Translational Allergy

Respiratory Medicine Journal